International Journal of

ADVANCED AND APPLIED SCIENCES

EISSN: 2313-3724, Print ISSN: 2313-626X

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 Volume 11, Issue 8 (August 2024), Pages: 19-23

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 Original Research Paper

Enhancing antibacterial activity through green synthesis of silver nanoparticles with salvia officinalis extracts

 Author(s): 

 Yara A. Altuwaijri, Maha A. Alshiekheid, Noura S. Aldosari, Mai A. Alghamdi, Nadine M. S. Moubayed *

 Affiliation(s):

 Department of Botany and Microbiology, College of Science, Female Campus, King Saud University, Riyadh 11451, Saudi Arabia

 Full text

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 * Corresponding Author. 

  Corresponding author's ORCID profile: https://orcid.org/0000-0002-4486-528X

 Digital Object Identifier (DOI)

 https://doi.org/10.21833/ijaas.2024.08.002

 Abstract

This study aimed to test the effectiveness of water-based extracts and green-synthesized silver nanoparticle extracts from the Salvia officinalis plant in killing bacteria. We used the agar well diffusion method to see how well these extracts could fight against both Gram-positive bacteria (Staphylococcus epidermidis and Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). To understand the properties of the nanoparticles, we analyzed them using a UV-VIS spectrophotometer and a scanning electron microscope (SEM). The results showed that both types of extracts were effective against the bacteria, with performance similar to the antibiotic chloramphenicol used as a benchmark. An interesting finding was that combining the plant extracts with the antibiotic or the silver nanoparticle extract with the antibiotic significantly enhanced the ability to stop bacterial growth in all tested strains. The Gram-positive bacteria were more affected than the Gram-negative ones, suggesting a potential way to overcome bacterial resistance.

 © 2024 The Authors. Published by IASE.

 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

 Keywords

 Salvia officinalis, Antibacterial activity, Synergistic potential, Silver nanoparticles, Green synthesis

 Article history

 Received 27 November 2023, Received in revised form 12 March 2024, Accepted 20 July 2024

 Acknowledgment 

This project was supported by Researchers Supporting Project number (RSP 2024R217) King Saud University, Riyadh, Saudi Arabia.

 Compliance with ethical standards

 Conflict of interest: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

 Citation:

 Altuwaijri YA, Alshiekheid MA, Aldosari NS, Alghamdi MA, and Moubayed NMS (2024). Enhancing antibacterial activity through green synthesis of silver nanoparticles with salvia officinalis extracts. International Journal of Advanced and Applied Sciences, 11(8): 19-23

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 Figures

 Fig. 1 Fig. 2 Fig. 3 Fig. 4 

 Tables

 Table 1 

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