Volume 8, Issue 2 (February 2021), Pages: 70-76

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 Original Research Paper

 Title: The process capability to fulfill specifications with an application in pharmaceutical tablets weights

 Author(s): Galal Abdulqader Ahmed Alashaari ^{1, 2,} *

 Affiliation(s):

 ¹College of Science and Humanities, Prince Sattam bin Abdulaziz University, Saudi Arabia
 ²Faculty of Commerce and Economics, Sana'a University, Sana'a, Yemen

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 * Corresponding Author. 

  Corresponding author's ORCID profile: https://orcid.org/0000-0001-9215-8574

 Digital Object Identifier: 

 https://doi.org/10.21833/ijaas.2021.02.010

 Abstract:

This research aims to identify one of the methods of statistical quality control, which is represented in the indicators of the Capability Process and explains its importance and how to use it for knowing the extension of the process to fulfill the specifications through several indicators with a statement that through practical application on one of the pharmaceutical products (Paramol Tablets Weights) one of the products of Yemeni Drug Company for Industry and Commerce (YEDCO). Hence, the results showed that the permits of process specifications of the tablet weight are equal to about 5 standard deviations, which is less than the standard practices, which are 8 standard deviations. Therefore, the capacity of the process for tablet weight is Cp<1, which is an undesirable state; because the production process is unable to satisfy the specifications. The CPK indicator shows that the process is decentralized and hence the inability of the process to fulfill the specifications; therefore, the company has to revise the limits of Paramol tablet weights specifications and to expand it as the company adopts numerous pharmacopeias in its operations. It must select the pharmacopeia that gives specifications which can make the process capability indicator and the index of process concentration in their standard state (Cp, Cpk=1.33mg). 

 © 2020 The Authors. Published by IASE.

 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

 Keywords: Process capability, Process capability index, Pharmaceutical tablets

 Article History: Received 12 July 2020, Received in revised form 24 September 2020, Accepted 1 October 2020

 Acknowledgment:

This publication was supported by the Deanship of Scientific Research, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia.

 Compliance with ethical standards

 Conflict of interest: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

 Citation:

  Alashaari GAA (2021). The process capability to fulfill specifications with an application in pharmaceutical tablets weights. International Journal of Advanced and Applied Sciences, 8(2): 70-76

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 Figures

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