International journal of

ADVANCED AND APPLIED SCIENCES

EISSN: 2313-3724, Print ISSN:2313-626X

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 Volume 6, Issue 7 (July 2019), Pages: 29-35

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 Original Research Paper

 Title: Clinical and cardiologic assessment of Anatolian shepherd dogs with asymptomatic degenerative mitral valve disease

 Author(s): Kursad Turgut 1, *, Amir Naseri 2, Mehmet Ege Ince 1, Havva Süleymanoğlu 1, Merve Ertan 1, Vedat Sağmanlıgil 1, Ismail Sen 2, 3

 Affiliation(s):

 1Faculty of Veterinary Medicine, Near East University, Nicosia, Northern Cyprus
 2Faculty of Veterinary Medicine, Selcuk University, Konya, Turkey
 3Faculty of Veterinary Medicine, Kyrgyz Turkish Manas University, Bishkek, Kyrgyzstan

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 * Corresponding Author. 

  Corresponding author's ORCID profile: https://orcid.org/0000-0001-8725-8044

 Digital Object Identifier: 

 https://doi.org/10.21833/ijaas.2019.07.004

 Abstract:

Degenerative mitral valve disease (DMVD) is the leading cause of cardiac disease and heart failure in the dog. Advanced age, breed and male gender are well-known risk factors for DMVD. The incidence of the disease in German Shepherds seems to be noteworthy. Early diagnosis of DMVD is related to the identification of a left apical systolic murmur, characteristic of MR in a dog. Dogs with DMVD had a low frequency of arrhythmias compared to other cardiac conditions. The goal of the study was (i) to evaluate the age and gender incidences of the asymptomatic Anatolian Shepherd Dogs (ASHs) with DMVD and, (ii) to investigate the importance of its clinical, radiological, electrocardiographic (ECG) findings and the correlations of those with some echo cardio logical measurements. 35 healthy ASHs (control group) and 38 ASHs with DMVD (experimental group) were used as the materials. The severity of cardiac disease was classified according to the American College of Veterinary Internal Medicine (ACVIM) consensus statement. Thirty two dogs (84.2%) were males and 6 dogs (15.8%) were females in the experimental group. The median age, the intensity of heart murmur and the severity of mitral regurgitation (MR) of the B2 dogs were bigger (p <0.05) than that of the B1 dogs. There was a positive correlation (P<0.05) between age and mitral valve lesions (MVLs). The clinical examination assessed by cardiac auscultation (murmur) was not correlated to MVLs, VHS, ECG findings and ARJ/LAA (P>0.05). The intensity of murmur was correlated to left ventricle to aorta ratio (LA/Ao) and it was not correlated (P>0.05) to MVLs, vertebral heart scale (VHS), ECG findings and regurgitant jet area to LA area ratio (ARJ/LAA). The correlations between ECG findings and VHS, along with, LA/Ao and ARJ/LAA were positive (P <0.05). In conclusion, aging and male gender may have a significant impact on DMVD progression in ASHs. Assessment of higher murmur in group B2 might be related to the progressive severity of the illnesses. The prevalence of arrhythmia was low in asymptomatic ASHs with DMVD. P-mitrale was noteworthy. 

 © 2019 The Authors. Published by IASE.

 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

 Keywords: Anatolian shepherd dog, Clinical assessment, Degenerative mitral valve disease, Echocardiography

 Article History: Received 14 February 2019, Received in revised form 28 April 2019, Accepted 30 April 2019

 Acknowledgement:

We are thankful to Dr. Enver Yazar for excellent assistance to statistical analyses.

 Compliance with ethical standards

 Conflict of interest:  The authors declare that they have no conflict of interest.

 Ethical approval:  

This study was approved by Ethic committee of Faculty of Veterinary Medicine, University of Selcuk (Permit number: 2012/053).
All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.

 Citation:

 Turgut K, Naseri A, and Ince ME et al. (2019). Clinical and cardiologic assessment of Anatolian shepherd dogs with asymptomatic degenerative mitral valve disease. International Journal of Advanced and Applied Sciences, 6(7): 29-35

 Permanent Link to this page

 Figures

 Fig. 1 Fig. 2 Fig. 3

 Tables

 Table 1 Table 2 Table 3 Table 4

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